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Symbol Name ID |
Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2 MGI:1917019 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal T cell apoptosis |
intestinal inflammation |
enlarged spleen |
spleen hyperplasia |
increased B cell number |
increased T cell number |
abnormal leukocyte morphology |
abnormal myeloid dendritic cell morphology |
abnormal spleen morphology |
increased spleen white pulp amount |
abnormal B cell physiology |
abnormal B cell activation |
decreased IgG2a level |
decreased IgG2b level |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal cytotoxic T cell physiology |
abnormal macrophage activation involved in immune response |
increased circulating interleukin-1 beta level |
increased circulating interleukin-10 level |
increased circulating interleukin-12 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
lymph node inflammation |
increased interferon-gamma secretion |
increased interleukin-1 beta secretion |
increased interleukin-12 secretion |
increased interleukin-17 secretion |
increased interleukin-2 secretion |
increased interleukin-4 secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
abnormal inflammatory response |
increased susceptibility to endotoxin shock |
chronic inflammation |
liver inflammation |
lung inflammation |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||
| Tnfaip8l2tm1Yhcn/Tnfaip8l2tm1Yhcn | |||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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